Seminari IRSJD: "Origen de l'ependimoma i del meduloblastoma (projecte MAGIC)"

• Ponent: Dr. Michael Taylor. Neurocirurgià i investigador en Neuro-oncologia del Sick Children's Hospital de Toronto

Resum

As a practicing pediatric neurosurgeon/clinician scientist, my research focuses on using tools from human genetics/genomics, and from mouse models to better understand the biology of pediatric brain tumors, particularly medulloblastoma and ependymoma. As someone who is comfortable in both the clinic and at the bench, I have a great deal to offer in the development of translational research for brain tumor research. I have previously described a number of the genetic events that are thought to drive the pathogenesis of medulloblastoma. More recently my laboratory has developed functional genomic mouse models of medulloblastoma to help better interpret our genomic studies of human medulloblastoma. I am the creator, and principal investigator of the Medulloblastoma Advanced Genomics International Consortium (MAGIC), through which I have collected >1600 frozen medulloblastomas from >75 high quality pediatric neuro-oncology centers from around the world. My clinical expertise, research experience in the field, and my current resources uniquely position me to contribute to studies on medulloblastoma and ependymoma.